What the 2-FDCK ?

2-FDCK Information Guide, (also known as 2-Fluorodeschloroketamine) is a dissociative substance of the arylcycohexylamine class. Other drugs in this class include PCP and ketamine, although 2-FDCK is more closely related to ketamine and is reported to have many similar effects. Created originally as a legal replacement for ketamine sometime around 2014, 2-FDCK first began being sold primarily through the online chemical research market in 2017 (1). Despite there being very few formal studies or clinical trials researching 2-FDCK, there are countless first-hand reports from members of the community we can draw upon to surmise what one should (and should not) expect from it. 

Chemistry of 2-FDCK Information Guide

2-Fluorodeschloroketamine, or 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone, is class as an arylcyclohexylamine drug. Arylcyclohexylamines drugs are named for their structures which include a cyclohexane ring bound to an aromatic ring along with an amine group. 2-FDCK contains a phenyl ring bonded to a cyclohexane ring substituted with a ketone group (cyclohexanone). An amino methyl chain (-N-CH3) is bound to the adjacent alpha carbon (R2) of the cyclohexanone ring. Additionally, the phenyl ring is substitute at R2 with a fluorine group.

2-Fluorodescholoroketamine is a chiral molecule and is often produce as a racemate. Des- is a prefix use in chemistry to denote the absence of a functional group (in this case “chloro”) hence 2-FDCK is name for containing a fluorine substitution at its phenyl ring rather than the chlorine which is in ketamine.

How does 2-FDCK work?

To get an understanding of the effects of 2-FDCK, it’s useful to dive into its chemical structure and see how it actually affects the brain. 

2-FDCK’s full chemical name is 2-(2-Fluorophenyl)-2-methylamino-cyclohexanone. Like all substances in its class (arylcycohexylamines), 2-FDCK has a cyclohexane ring bound to an aromatic ring along with an amine group. It also contains a phenyl ring bonded to its cyclohexane ring. (4) The only thing differentiating it from ketamine is that 2-FDCK contains a fluorine atom attached to the phenyl group, whereas ketamine contains a chlorine atom.

2-FDCK Information Guide & Subjective effects

Some people find 2-FDCK to be almost indistinguishable from ketamine, whereas others find that there are noticeable differences between the two. Here is a list of some of the most commonly reports effects of 2-FDCK: 

Physical effectsChild.svg

Urinary tract effects

Generally, In terms of its long-term health effects when used repeatedly and with excess for extended periods of time, 2-Fluorodeschloroketamine seems to exhibit almost identical bladder and urinary tract problems to those found within ketamine but to a lesser extent. This is because 2-Fluorodeschloroketamine is a little more potent than ketamine, meaning that less of the drug needs to be consume. Symptoms ofketamine-induced cystitis can become extremely serious and include:

  • Urinary frequency – Urinary frequency is the need to empty the bladder every few minutes.
  • Besides, Urinary urgency – This can be describe as a sudden, compelling need to urinate.
  • Urinary pressure – This is experience as a constant sensation of fullness in the bladder that is unrelieved by urination.
  • Pelvic and bladder pain – Pain can develop suddenly and severely, particularly as the bladder fills with urine.
  • Also,Hematuria – Hematuria is visible blood in the urine.
  • Incontinence – This is the leakage of urine.

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