Oxycontin is an opioid pain medication.
It is not known if Oxycontin is safe and effective in children younger than 18 years of age.
OxyContin may cause serious side effects including:
unusual thoughts or behavior,
loss of appetite,
worsening tiredness or weakness,
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Oxycontin. For more information, ask your doctor or pharmacist
Furthermore, OXYCONTIN should be prescrib only by healthcare professionals who are knowledgeable in the use of potent opioids for the management of chronic pain.
Equaly important, OXYCONTIN 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance to an opioid of comparable potency has been establish. Adult patients who are opioid tolerant are those receiving, for one week or longer, at least 60 mg oral morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone per day, or an equianalgesic dose of another opioid.
Besides, A strong prescription pain medicine that contains an opioid (narcotic) that is use to manage pain severe enough to require daily around-the-clock, long-term treatment with an opioid, when other pain treatments such as non-opioid pain medicines or immediate-release medicines do not treat your pain well enough or you cannot tolerate them.
Therefore, concomitant use of opioids with sedative medicines such as benzodiazepines or related drugs increases the risk of sedation, respiratory depression, coma and death because of additive CNS depressant effect. Inaddition, The dose and duration of concomitant use should be limite (see section 4.4). Drugs which affect the CNS include, but are not limit to: other opioids, gabapentinoids such as pregabalin, anxiolytics, hypnotics and sedatives (including benzodiazepines), antipsychotics, antidepressants, phenothiazines, anaesthetics, muscle relaxants, antihypertensives and alcohol.
Generally, Concomitant administration of oxycodone with serotonin agents, such as a Selective Serotonin Re-uptake Inhibitor (SSRI) or a Serotonin Norepinephrine Re-uptake Inhibitor (SNRI) may cause serotonin toxicity. The symptoms of serotonin toxicity may include mental-status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular abnormalities (e.g., hyperreflexia, incoordination, rigidity), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhoea). Oxycodone should be use with caution and the dosage may need to be reduce in patients using these medications.